Molecular Architecture of Spinal Cord Injury Protein Interaction Network
نویسندگان
چکیده
منابع مشابه
Molecular Architecture of Spinal Cord Injury Protein Interaction Network
Spinal cord injury (SCI) is associated with complex pathophysiological processes that follow the primary traumatic event and determine the extent of secondary damage and functional recovery. Numerous reports have used global and hypothesis-driven approaches to identify protein changes that contribute to the overall pathology of SCI in an effort to identify potential therapeutic interventions. I...
متن کاملGene expression signature analysis and protein-protein interaction network construction of spinal cord injury.
BACKGROUND The aim of this study was to investigate the gene expression profile of thoracic propriospinal neurons between post-injury rat and controls. MATERIALS AND METHODS Microarray dataset GSE20907 was downloaded from GEO database, including 12 Spinal Cord Injury (SCI) rat and 12 controls. Student's t test was employed to identified differentially expressed genes with a fold-change > 1.2....
متن کاملNatural Polyphenols and Spinal Cord Injury
Polyphenols have been shown to have some of the neuroprotective effects against neurodegenerative diseases. These effects are attributed to a variety of biological activities, including free radical scavenging/antioxidant and anti-inflammatory and anti-apoptotic activities. In this regard, many efforts have been made to study the effects of various well-known dietary polyphenols on spinal cord ...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0135024